Document Type : Original Article
Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran
Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
The increasing prevalence of metabolic syndrome on the one hand and its relationship with other chronic non-communicable diseases on the other hand has led to many studies to investigate the causes of metabolic syndrome or its components. This study was a case-control study that was performed on 160 men and women (80 individuals with metabolic syndrome and 80 healthy individuals) with a mean age of 47.8 years. In this study, demographic questionnaires, 147-item feed frequency, anthropometric and body composition information, blood pressure, and a fasting blood sample were taken from all subjects. All data were analyzed using SPSS software. People with metabolic syndrome had higher intakes of cereals, offal, fruits, oils, and snacks, and the differences were significant. Also, the mean atherogenic plasma index (AIP), cardiac risk ratio, and atherogenic coefficient (AC) in the group of patients with metabolic syndrome were higher significant than in the patients. However, there was no significant difference between the ORAC diet in the healthy and affected groups. There was also no association between dietary ORAC and AIP. Among the food groups, only nuts and viscera were not associated with the ORAC diet, but more food groups such as legumes, meats, fast foods, vegetables, spices, nuts, tea, coffee, and sugars were not associated with AIP. The results also showed that according to AIP values, 71.3% of healthy people are at risk of developing metabolic syndrome. According to the results, it seems that indicators related to the quality of dietary fat have an effective role in the development of metabolic syndrome and its components. However, the ORAC index did not have a significant effect on the development of the metabolic syndrome and its components and was associated only with the intake of many food groups.
- Swarup S, Goyal A, Grigorova Y, Zeltser R. Metabolic Syndrome. StatPearls. 2021.
- Reaven GM. The metabolic syndrome: Requiescat in pace. Clinical Chemistry. 2005; 51,931-8.
- Reaven GM. The metabolic syndrome: Is this diagnosis necessary? American Journal of Clinical Nutrition. 2006;83,1237-47.
- Kalan Farmanfarma K, Kaykhaei MA, Adineh HA, Mohammadi M, Dabiri S, Ansari-moghaddam A. Prevalence of metabolic syndrome in Iran: A meta-analysis of 69 studies. Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 2019;13(1):792-9.
- Fatahi A, Doosti-Irani A, Cheraghi Z. Prevalence and incidence of metabolic syndrome in Iran: a systematic review and meta-analysis. International Journal of Preventive Medicine. 2020;11,64.
- Saklayen MG. The global epidemic of the metabolic syndrome. Current Hypertension Reports. 2018;20(2):12.
- Haytowitz D, Bhagwat S. USDA Database for the oxygen radical absorbance capacity (ORAC) of selected foods, release 2. U.S. Department of Agriculture (USDA). 2010;10-48.
- Ballantyne CM, Hoogeveen RC, McNeill AM, Heiss G, Schmidt MI, Duncan BB, et al. Metabolic syndrome risk for cardiovascular disease and diabetes in the ARIC study. International Journal of Obesity. 2008;32(2):S21-4.
- Ahn S, Jun S, Shin J, Ham D, Choi E, Joung H. Association between intake of antioxidant vitamins and metabolic syndrome prevalence among korean adults (P24-001-19). Current Developments in Nutrition. 2019;(Suppl 1): nzz044.P24-001-19.
- Shin S, Lee S. Relation between the total diet quality based on Korean healthy eating index and the incidence of metabolic syndrome constituents and metabolic syndrome among a prospective cohort of Korean adults. The Korean Journal of Community Nutrition. 2020;25(1):61.
- Dobiášová M, Frohlich J. The plasma parameter log (TG/HDL-C) as an atherogenic index: Correlation with lipoprotein particle size and esterification rate inapob-lipoprotein-depleted plasma (FERHDL). Clinical Biochemistry. 2001;34(7):583-8.
- Millán J, Pintó X, Muñoz A, Zúñiga M, Rubiés-Prat J, Pallardo LF, et al. Lipoprotein ratios: Physiological significance and clinical usefulness in cardiovascular prevention. Vascular Health and Risk Management. 2009;5:757-65.
- Unger AL, Torres-Gonzalez M, Kraft J. Dairy fat consumption and the risk of metabolic syndrome: An examination of the saturated fatty acids in dairy. Nutrients. 2019;11(9): 2200.
- Guo XF, Li X, Shi M, Li D. N-3 polyunsaturated fatty acids and metabolic syndrome risk: A meta-analysis. Nutrients. 2017;9(7):703.
- Thomas GN, Ho SY, Janus ED, Lam KSL, Hedley AJ, Lam TH. The US National Cholesterol Education Programme Adult Treatment Panel III (NCEP ATP III) prevalence of the metabolic syndrome in a Chinese population. Diabetes Research and Clinical Practice. 2005;67(3):251-7.
- Madani Z, Moussavi Javardi M, Karandish M, Movahedi A. Promoting and updating food frequency questionnaire tool to measure food consumption and nutrient intake analysis. International Journal of Preventive Medicine. 2021;12(1):165.
- McBride J. High-ORAC foods may slow aging. United States Department of Agriculture. 1999;1-2.
- Haytowitz D, Bhagwat S. USDA database for the oxygen radical absorbance capacity (ORAC) of selected foods, release 2. U.S. Department of Agriculture (USDA). 2010;10-48.
- Dobiásová M. [AIP-atherogenic index of plasma as a significant predictor of cardiovascular risk: from research to practice]. Vnitr̆ní Lékar̆ství. 2006;52(1):64-71.
- Nunes SOV, Piccoli De Melo LG, Pizzo De Castro MR, Barbosa DS, Vargas HO, Berk M, et al. Atherogenic index of plasma and atherogenic coefficient are increased in major depression and bipolar disorder, especially when comorbid with tobacco use disorder. Journal of Affective Disorders. 2015;172:55-62.
- Faul F, Erdfelder E, Lang A-G, Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behavior Research Methods. 2007;39(2):175-91.
- Tian Y, Su L, Wang J, Duan X, Jiang X. Fruit and vegetable consumption and risk of the metabolic syndrome: A meta-analysis. Public Health Nutrition. Cambridge University Press; 2018;21,756-65.
- Esmaillzadeh A, Kimiagar M, Mehrabi Y, Azadbakht L, Hu FB, Willett WC. Fruit and vegetable intakes, C-reactive protein, and the metabolic syndrome. The American Journal of Clinical Nutrition. 2006;84(6):1489-97.
- Moussavi Javardi MS, Madani Z, Movahedi A, Karandish M, Abbasi B, javardi M sadat M, et al. The correlation between dietary fat quality indices and lipid profile with Atherogenic index of plasma in obese and non-obese volunteers: a cross-sectional descriptive-analytic case-control study. Lipids in Health and Disease. 2020;19(1):213.
- Moradinazar M, Sahargahi B, Naja F, Darbandi M, Moludi J, Hamzeh B, et al. The effect of the oil consumption pattern on atherogenic index of plasma: Evidence from a cohort study in west of Iran. ResearchSquare. 2021.
- Shab-Bidar S, Hosseini-Esfahani F, Mirmiran P, Hosseinpour-Niazi S, Azizi F. Metabolic syndrome profiles, obesity measures and intake of dietary fatty acids in adults: Tehran lipid and glucose study. Journal of Human Nutrition and Dietetics. 2014;27(Suppl2):98-108.
- Lee YS, Cho Y, Shin M-J. Dietary very long chain saturated fatty acids and metabolic factors: Findings from the Korea national health and nutrition examination survey 2013. Clinical Nutrition Research. 2015;4(3):182.
- Park YW, Zhu S, Palaniappan L, Heshka S, Carnethon MR, Heymsfield SB. The metabolic syndrome: Prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994. Archives of Internal Medicine. 2003;163(4):427-36.
- Kim H, Stote KS, Behall KM, Spears K, Vinyard B, Conway JM. Glucose and insulin responses to whole grain breakfasts varying in soluble fiber, β-glucan: A dose response study in obese women with increased risk for insulin resistance. European Journal of Nutrition. 2009;48(3):170-5.
- Kratz M, Baars T, Guyenet S. The relationship between high-fat dairy consumption and obesity, cardiovascular, and metabolic disease. European Journal of Nutrition. 2013; 52,1-24.
- Julibert A, Bibiloni MDM, Mateos D, Angullo E, Tur JA. Dietary fat intake and metabolic syndrome in older adults. Nutrients. 2019;11(8).
- Zujko ME, Waśkiewicz A, Witkowska AM, Szcześniewska D, Zdrojewski T, Kozakiewicz K, et al. Dietary total antioxidant capacity and dietary polyphenol intake and prevalence of metabolic syndrome in Polish adults: A nationwide study. Oxidative Medicine and Cellular Longevity. 2018;2018.
- Dzięgielewska-Gęsiak S, Wyszomirska K, Fatyga E, Wysocka E, Muc-Wierzgoń M. The role of oxidant-antioxidant markers and resistin in metabolic syndrome elderly individuals. Science Progress. 2021;104(2):1-14.
- Hermsdorff HHM, Puchau B, Volp ACP, Barbosa KB, Bressan J, Zulet MÁ, et al. Dietary total antioxidant capacity is inversely related to central adiposity as well as to metabolic and oxidative stress markers in healthy young adults. Nutrition & Metabolism. 2011;8:59